The eMERGE Network brings together researchers with a wide range of expertise in genomics, statistics, ethics, informatics, and clinical medicine from leading medical research institutions across the country. Each center participating in the consortium is uniquely situated to provide critical resources to this highly collaborative and productive network. Each site combines a biobank or study cohort with extensive genomic data and access to clinical data derived from electronic medical records. Sites are geographically dispersed and have diverse patient populations, including two sites focusing specifically on pediatrics. Member sites include:
Participant Sites: Project Overview
Click on each site below for more information:
Children’s Hospital of Philadelphia (CHOP)
Principal Investigator: Hakon Hakonarson, MD, PhD
Cincinnati Children’s Hospital Medical Center (CCHMC)
Principal Investigator: John Harley, MD, PhD
Principal Investigators: Chunhua Weng, PhD, MS; Ali Gharavi, MD; George Hripcsak, MD, MS
Principal Investigators: Marc Williams, MD; Marylyn Ritchie, PhD
Principal Investigators: Elizabeth Karlson, MD; Shawn Murphy, MD, PhD; Jordan Smoller, MD, ScD; Scott Weiss, MD, MS
Kaiser Permanente Washington with the University of Washington and the Fred Hutchinson Cancer Research Center (KPW/UW)
Principal Investigators: Eric Larson, MD, MPH (KPW); Gail Jarvik, MD, PhD (UW)
Mayo Clinic (Mayo)
Principal Investigators: Iftikhar Kullo, MD; Stephen Thibodeau, PhD
Meharry Medical College
Principal Investigator: Samuel Adunyah, PhD
Meharry Medical College (MMC) is the nation’s largest private, independent, historically black academic health center dedicated solely to educating minority and other health professionals. The Meharry Translational Research Center (MeTRC) was established to expand and strengthen the overall research infrastructure for conducting and promoting clinical and translational research in health disparities, with a major emphasis to reduce or eliminate disease burden in minorities regarding inflammatory diseases, HIV/AIDS, diabetes/obesity, cancer and neurological diseases. MeTRC has synergized with several ongoing research initiatives, including: Research Centers in Minority Institutions (NIMHD), Meharry-Vanderbilt Alliance, Vanderbilt-Meharry CTSA (NCATS), MMC Center for AIDS Health Disparities Research, MMC Center for Women’s Health Research, and Meharry-Vanderbilt-Tennessee State University Cancer Partnership (NCI).
Meharry will strengthen eMERGE’s diversity by recruiting from a predominantly African American population (n=500) and obtaining blood samples for DNA extraction for germ-line sequencing. Meharry is targeting affected and high-risk cohorts of breast cancer, prostate cancer, colorectal cancer and lung cancer. Meharry aims to return results to patients and physicians through the electronic medical record with the goal of improving health outcomes within the community.
Northwestern University (NU)
Principal Investigators: Rex Chisholm, PhD; Maureen Smith, MS
Vanderbilt University Medical Center (VUMC)
Principal Investigators: Dan Roden, MD; Josh Denny, MD, MS
eMERGE Network Coordinating Center (CC)
Principal Investigators: Josh Peterson, MD, MPH (VUMC)
–Organize and track program-wide activities: maintain and disseminate network metrics, including the master calendar, network timelines, publications lists, membership contact information, and email distribution lists.
–Event planning support: organize face-to-face Steering Committee meetings and other in-person events.
–Facilitate scheduling and organization of committees and activities: schedule meetings and events for the Steering Committee, working groups and subgroups.
–Communications support: participate in all conference calls; collaborate with leadership to develop meeting agendas, and generate & distribute meeting minutes.
Central Sequencing & Genotyping Centers (CSGs)
Click on each site below for more information:
Partners Healthcare with Broad Institute
Principal Investigators: Heidi Rehm, PhD (Partners); Niall Lennon, PhD (Partners/Broad)
Baylor College of Medicine Human Genome Sequencing Center (HGSC)
Principal Investigators: Richard Gibbs, PhD
External Scientific Panel
Click on the site below for more information:
University of North Carolina, Chapel Hill
Chairperson: Howard McLeod, PharmD
- Eta Berner, Ed.D – University of Alabama at Birmingham
- Kim Doheny, Ph.D. – Johns Hopkins University
- Gerardo Heiss, MD, PhD – University of North Carolina
- Stan Huff, MD – InterMountain Healthcare
- Howard McLeod, PharmD – University of North Carolina
- Lisa Parker, PhD – University of Pittsburgh
- Vandana Shashi, M.D. – Duke University